Arcade

Interaction Defuse

Disarm polypharmacy interactions

Choose a case (6)

Statin + macrolide

Patient on simvastatin 40 mg and a new 5-day course of clarithromycin 500 mg BD.

Warfarin + NSAID

Patient stable on warfarin requests OTC ibuprofen for chronic knee pain.

ACEi + K-sparing diuretic + K supplement

Heart failure patient on lisinopril, spironolactone, and a new potassium supplement.

Metformin + iodinated contrast

Diabetic patient on metformin booked for contrast CT tomorrow.

Levothyroxine + calcium

Patient on levothyroxine started on calcium carbonate for osteoporosis prevention.

SSRI + tramadol

Patient on sertraline asks for tramadol for acute back pain.